Nanoneurology - Drug Delivery across the Brain Protective Barriers
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چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: AD: Alzheimer Disease; Apo-E: ApoLipoprotein-E; BBB: Blood Brain Barrier; Brainpeps: BBB Peptide Database; CNS: Central Nervous System; CSF: CerebroSpinal Fluid; EPIC: Engineered Peptide Compound; HAD: HIVAssociated Dementia; HIFU: High Intensity Focused Ultrasound; HIV: HIV Encephalitis; HIV: Human Immunodeficiency Virus; LPR: Lipoprotein Related Protein; MEN: Magneto-Electric Nanoparticles; MS: Multiple Sclerosis; ND: Nano Device; NP: Nano Particle; PD: Parkinson Disease; P-gP: P-Glycoprotein; PLGA: Poly Lactic co-Glycolic Acid; PNS: Peripheral Nervous System; RNA: Ribo Nucleic Acid
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Current approaches to enhance CNS delivery of drugs across the brain barriers
Although many agents have therapeutic potentials for central nervous system (CNS) diseases, few of these agents have been clinically used because of the brain barriers. As the protective barrier of the CNS, the blood-brain barrier and the blood-cerebrospinal fluid barrier maintain the brain microenvironment, neuronal activity, and proper functioning of the CNS. Different strategies for efficien...
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